Publications
P.L.E.A.S.E.® Research
Laser Application
Laser-assisted intradermal application of mRNA-loaded nanocarriers for minimally invasive ("needle free") vaccination via the skin.
Dissertation from Lena Kliesch, Faculty of Science and Technology, University of Saarland, 2024
Cryogenically cooled Fe:ZnSe-based chirped pulse amplifier at 4.07 µm
Author: Z. Alphonse Marra, Yi Wu, Fangjie Zhou, and Zenghu Chang
Optics Express, Vol. 31, Issue 8, pp. 13447-13454 (2023)
Compact all-solid-state femtosecond Yb amplifier using a high-brightness multi-watt tapered laser diode
ScienceDirect - 2023, Sep. 01..
Laser-assisted intradermal delivery of a microparticle vaccine for respiratory syncytial virus induces a robust immune response
Ipshita Menon, Sang Moo Kang , Keegan Braz Gomes, Mohammad N Uddin, Martin D'Souza
Vaccine, 2023 Feb 3
PMID: 36631361 DOI: 10.1016/j.vaccine.2023.01.002
Delivery of Er:YAG laser radiation with repetition rate up to 150 Hz by a hollow glass waveguide
Author: Michal Nemec, Helena Jelinkova, Jan Sulc, Katsumasa Iwai, Hiroyuki Takaku, Mitsunobu Miyagi
Paper 12399-42
31 January 2023, Moscone Center, Level 2 West
Context-dependent function of TSLP and IL-1β in skin allergic sensitization and atopic march
Justine Segaud, Wenjin Yao, Pierre Marschall, François Daubeuf, Christine Lehalle, Beatriz German, Pierre Meyer, Pierre Hener, Cécile Hugel, Eric Flatter, Marine Guivarch, Laetitia Clauss, Stefan F Martin, Mustapha Oulad-Abdelghani, Mei Li
PMID: 36050303 PMCID: PMC9437001 DOI: 10.1038/s41467-022-32196-1
Pantec Er:YAG laser - brain surgery with vascular specific coagulation
Autor: Nitesh Katta PhD
Beckman Laser Institute
University of California in Irvine, East Irvine, Kalifornien, USA
Arnold D. Estrada PhD, Austin B. McElroy MS, Thomas E. Milner PhD
Wiley, August 10, 2022
https://doi.org/10.1002/lsm.23591
Phase I Study to Assess Safety of Laser-Assisted Topical Administration of an Anti-TNF Biologic in Patients With Chronic Plaque-Type Psoriasis
Martin Bauer, Edtih Lackner, Peter Matzellner, Valentin Al Jalali, Sahra Pajenda, Vincent Ling, Christof Böhler, Werner Braun, Reinhard Braun, Maximilian Boesch, Patrick M. Brunner, Markus Zeitlinger
Front.Med, July 16, 2021
https://doi.org/10.3389/fmed.2021.712511
Comparative ex vivo Investigations on the Cutting Quality of the CO2 Laser and the Diode Pumped Er:YAG Laser
Holger Wurm, Patrick Johannes Schuler, Florian Hausladen, René Graesslin, Thomas Karl Hoffmann, Karl Stock and Elisabeth Friederike Reins
ORIGINAL RESEARCH article, Front. Surg., 14 December 2021
Copyright 2021 Wurm, Schuler, Hausladen, Graesslin, Hoffmann, Stock and Reins. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
Laser-facilitated epicutaneous immunization of mice with SARS-CoV-2 spike protein induces antibodies inhibiting spike/ACE2 binding
Sandra Scheiblhofer, Stephan Drothler, Werner Braun, Reinhard Braun, Maximilian Bösch, Richard Weiss
Vaccine, June 26, 2021
https://doi.org/10.1016/j.vaccine.2021.06.068
Primary investigations on defined thermal effects on soft tissue using a diode pumped Er:YAG laser system
Stock K, Meitinger D, Hausladen F, Stegmayer Th, Wurm H
Proc. SPIE 10876, Optical Interactions with Tissue and Cells XXX, 108760Y (1 March 2019);
doi: 10.1117/12.2509674
Copyright 2019 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Laser facilitated epicutaneous peptide immunization using dry patch technology
Sandra Scheiblhofer, Stephan Drothler, Werner Braun, Reinhard Braun, Maximilian Bösch, Richard Weiss
bioRxiv preprint, April 28, 2021
https://doi.org/10.1101/2021.04.27.441719
Feasibility Assessment of Optical Coherence Tomography-Guided Laser Labeling in Middle Cranial Fossa Approach
Mohebbi S, Lexow J, Fuchs A, Rau Th, Tauscher S, Mirsalehi M, Hosseini S, Ortmaier T, Lenarz Th, Majdani O
Iranian Journal of Otorhinolaryngology, Volume 30, issue 6 - Serial number 101, November and December 2018, Page 321 -327
doi: 10.22038/IJORL.2018.30275.1991
Laser-assisted epicutaneous immunization to target human skin dendritic cells
Christoph H. Tripp, Hermann Voit, Angela An, Magdalene Seidl-Philipp, Johanna Krapf, Stephan Sigl, Nikolaus Romani, Barbara Del Frari, Patrizia Stoitzner
Experimental Dermatology, April 02, 2021
https://doi.org/10.1111/exd.14346
Selective removal of dental calculus with a diode-pumped Er:YAG laser
Fried W. A., Cha K. H., Darling C. L., Fried D
Proc. SPIE 104857, Lasers in Dentistry XXV, 108570M (28 February 2019)
doi: 10.1117/12.2512937
Copyright 2019 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Laser irradiation of ocular tissues to enhance drug delivery
Raghu Raj Singh Thakur, Samer Adwan, Ismaiel Tekko, Karim Soliman, Ryan F. Donnelly
Int. Journal of Pharmaceutics. 2021 March; Volume 596, 120282
doi: 10.1016/j.ijpharm.2021.120282
High efficient bone ablation with diode pumped Erbium and Thulium lasers including different delivery fibers: a comparative in vitro study
Stock K, Hausladen F, Stegmayer T, Wurm H
Proc. SPIE 10488, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII, 104880U (2018), doi:10.1117/12.2290336
Copyright 2018 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Laser-facilitated epicutaneous immunotherapy with hypoallergenic beta-glucan neoglycoconjugates suppresses lung inflammation and avoids local side effects in mouse model of allergic asthma
Evgeniia Korotchenko, Viktoria Schießl, Sandra Scheiblhofer, Mario Schubert, Elfriede Dall, Isabella A. Joubert, Helen Strandt, Theresa Neuper, Muamera Sarajilic, Renate Bauer, Mark Geppert, David Joedicke, Sabrina Wildner, Susanne Schaller, Stephan Winkler, Gabriele Gadermaier, Jutta Horejs-Hoeck, Richard Weiss
Allergy. 2021 Jan;76(1):210-222
doi: 10.1111/all.14481
High-energy diode side-pumped Er:YLF laser generating 100 mJ @ 100 Hz
Messner M, Heinrich A, Hagen C, Unterrainer K
Proc. SPIE 10511, Solid State Lasers XXVII: Technology and Devices, 105110J (2018)
doi:10.1117/12.2288134
Copyright 2018 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Laser-facilitated epicutaneous immunotherapy with depigmented house dust mite extract alleviates allergic responses in a mouse model of allergic lung inflammation
Evgeniia Korotchenko, Raquel Moya, Sandra Scheiblhofer, Isabella A. Joubert, Jutta Horejs-Hoeck, Michael Hauser, David Calzada, Victor Iraola, Jerónimo Carnés, Richard Weiss
Allergy. 2020 May;75(5):1217-1228
doi: 10.1111/all.14164
High-energy diode side-pumped Er:LiYF4 laser
Messner M, Heinrich A, Unterrainer K
Applied Optics, Vol. 57, Issue 6, pp 1497-1503 (2018)
doi:10.1364/AO.57.001497
Copyright 2018 Optical Society of America
Dual function of Langerhans cells in skin TSLP-promoted Tfh cell differentiation in mouse atopic dermatitis
Pierre Marschall, Ruicheng Wei, Justine Segaud, Wenjin Yao, Pierre Hener, Beatriz Falcon German, Pierre Meyer, Cecile Hugel, Grace Ada Da Silva, Reinhard Braun, Daniel H Kaplan, Mei Li
J Allergy Clin Immunol, 2020 Oct 14; S0091-6749(20)31408-1
doi: 10.1016/j.jaci.2020.10.006
Seeing laser scalpel: a novel monolithic high-power diode pumped Tm:YAG laser system at 2.02 µm with double-clad fiber combined OCT
Messner M, Heinrich A, Hagen C, Unterrainer K
Proc. SPIE 10054, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XV, 100540X (February 14,2017), doi:10.1117/12.2250779
Copyright 2017 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Targeted cutaneous delivery of etanercept using Er:YAG fractional laser ablation
del Río Sancho S, Lapteva M, Sonaje K, Böhler C, Ling V, Boehncke W, Kalia Y
International Journal of Pharmaceutics, Volume 580, 30 April 2020
doi: 10.1016/j.ijpharm.2020.119234
Investigations on the potential of a novel diode pumped Er:YAG laser system at high mean laser power for hard tissue preparation in dentistry
Hausladen F, Wurm H, R Hibst, K Stock
Proc. SPIE 10044, Lasers in Dentistry XXIII, 100440B (February 10,2017)
doi:10.1117/12.2252921
Copyright 2017 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Epidermal micro-perforation potentiates the efficacy of epicutaneous vaccination
Hervé P, Dhelft V, Plaquet C, Rosseaux A, Bouzereau A, Gaulme L, Tilleul S, Ligouis M, Donne N, Lambert P, Hong-Thai P, Wijagkanalan W, Sampson H A, Mondoulet L
Journal of Controlled Release, Volume 298, 28 March 2019, Pages 12-26
doi: 10.1016/j.jconrel.2019.02.004
Selective removal of natural caries lesions from dentin and tooth occlusal surfaces using a diode-pumped Er:YAG laser
Jew J., Chan K.H., Darling C.L., Fried D.
Proc. SPIE 10044, Lasers in Dentistry XXIII, 100440I (February 8,2017)
doi:10.1117/12.2256728
Copyright 2017 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Fractional laser ablation for the targeted cutaneous delivery of an anti-CD29 monoclonal antibody - OS2966
Lapteva M, del Río Sancho S, Wu E, Carbonell WS, Böhler C, Kalia YN
Sci Rep. 2019 Jan 31; 9(1):1030. doi: 10.1038/s41598-018-36966-0
Influence of multi-wavelength laser irradiation of enamel and dentin surfaces on surface morphology and permeability
Chang NY.N., Jew J., Simon J.C., Chan K.H., Lee R.C., Fried W.A., Cho J., Darling C.L., Fried D.Proc. SPIE 10044, Lasers in Dentistry XXIII, 100440H (February 8,2017), doi:10.1117/12.2256734
Copyright 2017 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Parameters in fractional laser assisted delivery of topical anesthetics: Role of laser type and laser settings.
Meesters AA, Nieboer MJ, Kezic S, de Rie MA, Wolkerstorfer A
Lasers Surg Med, 2018 May 7; doi: 10.1002/lsm.22936
Selective removal of dental composite with a diode-pumped Er:YAG laser
William A. Fried, Kenneth H. Chan, Cynthia L. Darling, Daniel Fried
Proc. SPIE Int Soc Opt Eng. 2016 Feb 9692: 96920S , doi:10.1117/12.2218645
Copyright 2016 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Lack of dermal penetration of topically applied gentamicin as pharmacokinetic evidence indicating insufficient efficacy.
Oesterreicher Z, Lackner E, Jäger W, Höferl M, Zeitlinger M
J Antimicrob Chemother, 2018 Aug 2; doi: 10.1093/jac/dky274
High brightness diode pumped Er:YAG laser system at 2.94 µm with nearly 1 kW peak power
Manuel Messner, Arne Heinrich, Clemens Hagen, Karl Unterrainer
Proc. SPIE 9726, Solid State Lasers XXV: Technology and Devices, 972602 (March 17, 2016)
doi:10.1117/12.2209098
Copyright 2016 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Needle-free cutaneous delivery of living human cells by Er:YAG fractional laser ablation.
Yu J, Dubey S, Kalia YN
Expert Opin Drug Deliv. 2018 Jun;15(6):559-566. doi: 10.1080/17425247.2018.1472570
Endoluminal non-contact soft tissue ablation using fiber-based Er:YAG laser delivery
Dennis Kundrat, Alexander Fuchs, Andreas Schoob, Lüder A. Kahrs, Tobias Ortmaier
Proc. SPIE 9702, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVI, 97020E (March 7, 2016) , doi:10.1117/12.2211796
Copyright 2016 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Application of water-soluble polyvinyl alcohol-based film patches on laser microporated skin facilitates intradermal macromolecule and nanoparticle delivery.
Engelke L, Winter G, Engert J
Eur J Pharm Biopharm, 2018 Juli;128:119-130. doi: 10.1016/j.ejpb.2018.04.008
Primary investigations on the potential of a novel diode pumped Er:YAG laser system for middle ear surgery
Karl Stock, Holger Wurm, Florian Hausladen
Proc. SPIE 9689, Photonic Therapeutics and Diagnostics XII, 96892K (March 1, 2016)
doi:10.1117/12.2213105
Copyright 2016 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Delivery of Methotrexate and Characterization of Skin Treated by Fabricated PLGA Microneedles and Fractional Ablative Laser.
Nguyen HX, Banga AK
Pharm Res, 2018 Feb, 21;35(3):68. doi: 10.1007/s11095-2369-6
Mass Spectrometry of Levitated Droplets by Thermally Unconfined Infrared-Laser Desorption
Carsten Warschat, Arne Stindt, Ulrich Panne, Jens Riedel
Analytical Chemistry, 2015, 87 (16), pp 8323–8327 (August 3, 2015)
doi:10.1021/acs.analchem.5b01495
Copyright © 2015 American Chemical Society
Qualitative and quantitative analysis of lateral diffusion of drugs in human skin.
Nguyen HX, Puri A, Bhattaccharjee SA, Banga AK
Int J Pharm, 2018 Jun 10; 544(1):62-74, doi: 10.1016/j.ijpharm.2018.04.013
Fast and automatic depth control of iterative bone ablation based on optical coherence tomography data
Alexander Fuchs, Steffen Pengel, Jan Bergmeier, Lüder A. Kahrs, Tobias Ortmaier
Proc. SPIE 9542, Medical Laser Applications and Laser-Tissue Interactions VII (15 July 2015)
doi:10.1117/12.2183695
Copyright 2015 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Transdermal delivery of human growth hormone via laser-generated micropores.
Yang Song, Karishma Hemmady, Ashana Puri, Ajay K. Banga
Drug Deliv Transl Res., 2018 Apr; 8(2):450-460, doi: 10.1007/s13346-017-0370-y
Efficient bone cutting with the novel diode pumped Er:YAG laser system: in vitro investigation and optimization of the treatment parameters
Stock K, Diebolder R, Hausladen F, Hibst R
Proc. SPIE 8926, Photonic Therapeutics and Diagnostics X, 89263P (March 4, 2014)
doi:10.1117/12.2039648
Copyright 2014 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Synergistic effects of dendritic cell targeting and laser-microporation on enhancing epicutaneous skin vaccination efficacy.
Machado Y, Duinkerken S, Hoepflinger V, Mayr M, Korotchenko E, Kurtaj A, Pablos I, Steiner M, Stoecklinger A, Lübbers J, Schmid M, Ritter U, Scheiblhofer S, Ablinger M, Wally V, Hochmann S, Raninger AM, Strunk D, van Kooyk Y, Thalhamer J, Weiss R
J Control Release, 2017 Sep 14; 266:87-99, doi: 10.1016/j.conrel.2017.09.020
Investigations on the potentail of a low power diode pumped Er:YAG laser system for oral surgery
Stock K, Diebolder R, Hausladen F, Hibst R
Proc. SPIE 9306, Lasers in Dentistry XXI, 930605 (February 24, 2015)
doi:10.1117/12.2078723
Copyright 2015 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Skin vaccination via fractional infrared laser ablation - Optimization of laser-parameters and adjuvantation
S Scheiblhofer, A Strobl, V Hoepflinger, T Thalhamer, M Steiner, J Thalhamer, R Weiss
Vaccine, Jan. 2017, pii: S0264-410X(17)30058-0, DOI:10.1016/j.vaccine.2016.11.105, PMID: 28117172
Aplanatic beam shaping for diffraction limited beam circularization of tapered laser diodes
Heinrich A, Hagen C, Harlander M, Nussbaumer B
Proc. SPIE 8965, High-Power Diode Laser Technology and Applications XII, 89650W (March 7, 2014)
doi:10.1117/12.2039355
Copyright 2014 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Potential of nanoparticles for allergen-specific immunotherapy - use of silica nanoparticles as vaccination platform
S Scheiblhofer, Y Machado, A Feinle, J Thalhamer, N Hüsing, R Weiss
Expert Opinion on Drug Delivery, Dec. 2016, 13(12):1777-1788, DOI:10.1080/17425247.2016.1203898, PMID: 27321476
High brightness diode pumped Er:YAG laser system at 2.94 µm with 400W peak power
Harlander M, Heinrich A, Hagen C, Nussbaumer B
Proc. SPIE 8959, Solid State Lasers XXIII: Technology and Devices, 895908 (February 28, 2014)
doi:10.1117/12.2037746
Copyright 2014 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Laser-facilitated epicutaneous immunotherapy to IgE-mediated allergy
MN Kumar, C Zhou, MX Wu
Journal of Controlled Release, Aug. 2016, 235:82-90, DOI:10.1016/j.conrel.2016.05.057, PMID: 27235977
Automatisierte Überwachung der Laserosteotomie mittels optischer Kohärenztomographie
Fuchs A, Kundrat D, Schultz M, Krüger A, Ortmaier T
Publication Date: 2012.11.15
Best Paper Award - CURAC - Deutsche Gesellschaft für Computer- und Roboterassistierte Chirurgie e.V.
>> For more information please contact 3um@pantec.com
Fractional Laser Ablation for the Cutaneous Delivery of Triamcinolone Acetonide from Cryomilled Polymeric Microparticles: Creating Intraepidermal Drug Depots
M Singhal, S Del Rio-Sancho, K Sonaje, YN Kalia
Mol Pharm, Feb. 2016;13(2):500-11, DOI:10.1021/acs.molpharmaceut.5b00711, PMID: 26731121
Investigations on the potential of a novel diode pumped Er:YAG laser system for dental applications
Stock K, Hausladen F, Hibst R
Proc. SPIE 8208, Lasers in Dentistry XVIII, 82080D (February 9, 2012)
doi:10.1117/12.908382
Copyright 2012 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Ablative fractional laser enhances MAL-induced PpIX accumulation: Impact of laser channel density, incubation time and drug concentration
C.S. Haak, K. Christiansen, A.M. Erlendsson, E.H. Taudorf, D. Thaysen-Petersen, H.C. Wulf, M. Haedersdal
Journal of Photochemistry & Photobiology, B: Biology, June 2016, 159:42-8, DOI:10.1016/j.iphotobiol.2016.03.021
Using laser microporation to improve transdermal delivery of diclofenac: Increasing bioavailability and the range of therapeutic applications.
Bachhav YG, Heinrich A, Kalia YN.
Eur J Pharm Biopharm. 2011 Aug; 78(3):408-14. Epub 2011 Mar 21.
PMID: 21397689
Practical approach to the use of daylight photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: a European consensus
Morton CA, Wulf HC, Szeimies RM, Gilaberte Y, Basset-Sequin N, Sotiriou E, Piaseriao S, Hunger RE, Baharlou S, Sidoroff A, Braathen LR
J Eur Acad Dermatol Venerol, Sept. 2015;29(9):1718-23, DOI:10.1111/jdv.12974, PMID: 25627399
High-power, diode-pumped Er:YAG lasers for soft and hard tissue applications
Heinrich A, Hagen C, Vizhanyo A, Krammer P, Summer S, Gross S, Boehler C, Bragagna T.
Proc. SPIE 8092, Medical Laser Applications and Laser-Tissue Interactions V, 80921C (June 02, 2011)
doi:10.1117/12.888255
Copyright 2011 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Ablative fractional laser alters biodistribution of ingenol mebutate in the skin
A.M. Erlendsson, E.H. Taudorf, A.H. Eriksson, C.S. Haak, J.R. Zibert, U. Paasch, R.R. Anderson, M. Haedersdal
Arch Dermatol Res, Aug. 2015,;307(6):515:-22, DOI:10.1007/s00403-015-1561, PMID:25832754
30 mJ, TEM00, high repetition rate, mechanically Q-switched Er:YAG laser operating at 2940 nm
Skorczakowski M, Pichola W, Swiderski J, Nyga P, Galecki L, Maciejewska M, Zajac A, Gross S, Heinrich A, Bragagna T, Kasprzak J.
Opto-Electronics Review, Volume 19, Issue 2, pp.206-210
DOI: 10.2478/s11772-011-0011-9
Laser-Assisted Intradermal Delivery of Adjuvant-Free Vaccines Targeting XCR1+ Denditric Cells Induces Potent Antitumoral Responses
D. Terhorst, E. Fossum, A Baranska, S. Tamoutounour, C. Malosse, M. Garbani, R. Braun, E. Lechat, R. Crameri, B. Bogen, S. Henri, B. Malissen
The Journal of Immunology, May 2015, DOI:10.4049/jimmunol.1500564
High power, diode side pumped Er:YAG lasers
Heinrich A, Bragagna T.
Lasers and Electro-Optics Europe (CLEO EUROPE/EQEC), 2011 Conference and 12th European Quantum Electronics Conference
Issue Date: 22-26 May 2011 On page(s): 1 - 1, Location: Munich, ISSN: Pending
Print ISBN: 978-1-4577-0533-5
INSPEC Accession Number: 12189945
Digital Object Identifier: 10.1109/CLEOE.2011.5942493
Date of Current Version: 07 Juli 2011
Combination of ablative fractional laser and daylight-mediated photodynamic therapy for actinic keratosis in organ transplant recipients - a randomized controlled trial
K. Togsverd-Bo, U. Lei, A.M. Erlendsson, E.H. Taudorf, P.A. Philipsen, H.C. Wulf, L. Skov and M. Haedersdal
British Journal of Dermatology, Feb. 2015, DOI:10.1111/bjd.13222, PMID: 24975199
Next generation Er:YAG fractional ablative laser
Heinrich A, Hagen C, Vizhanyo A, Krammer P, Summer S, Gross S, Bragagna T, Boehler C.
Proc. SPIE 7883, Photonic Therapeutics and Diagnostics VII, 78830M (February 17, 2011)
doi:10.1117/12.873522
Copyright 2011 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
The origins and functions of dendritic cells and macrophages in the skin
B Malissen, S Tamoutounour, S Henri
Nat Rev Immunol, June 2014;14(6):417-28, DOI:10.1038/nri3683, PMID: 24854591
High power, diode pumped Er:YAG for dentistry
Hagen C, Heinrich A, Nussbaumer B
Proc. SPIE 7884, Lasers in Dentistry XVII, 78840I (February 17, 2011) , doi:10.1117/12.873549
Copyright 2011 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Next generation intra- and transdermal therapeutic systems: Using non- and minimally-invasive technologies to increase drug delivery into and across the skin
T Gratieri, I Alberti, M Lapteva, YN Kalia
European Journal of Pharmaceuticical Sciences, Dec. 2013; 50(5):609-22, DOI:10.1016/j.ejps.2013.03.019, PMID: 23567467
Miniaturized high power Er:YAG solid state laser pumped by a single laser diode bar
Krejci M, Heinrich A, Mueller J, Bragagna T, Lichtenstein N.
Proc. SPIE 7912, Solid State Lasers XX: Technology and Devices, 79121D (February 15, 2011)
doi:10.1117/12.873576
Copyright 2011 Society of Photo-Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.
Using controlled laser-microporation to increase transdermal delivery of prednisone.
Yu J, Bachhav YG, Summer S, Heinrich A, Bragagna T, Boehler C, Kalia YN.
J Control Release. 2010 Nov 20; 148(1):e71-3. No abstract available.
PMID: 21529638
Controlled intra- and transdermal protein delivery using a minimally invasive Erbium:YAG fractional laser ablation technology
YG Bachhav, A Heinrich, YN Kalia
European Journal of Pharmaceutics and Biopharmaceutics, June 2013; 84(2):355-64, DOI:10.1016/j.ejpb.201211.018, PMID: 23207321
Laser microporation of the skin: prospects for painless application of protective and therapeutic vaccines
S Scheiblhofer, J Thalhamer, R Weiss
Expert Opinion Drug Delivery, June 2013; 10(6):761-73, DOI:10.1517/17425247.2013.773970, PMID: 23425032
Mid-infrared Q-switched Er:YAG laser for medical applications
Skorczakowski M, Swiderski J, Pichola W, Nyga P, Zajac A, Maciejewska M, Galecki L, Kasprzak J, Gross S, Heinrich A, Bragagna T.
Publication date: 2010.01.07
Laser Physics Letters
DOI: 10.1002/lapl.201010019
Transcutaneous immunotherapy via laser-generated micropores efficiently alleviates allergic asthma in Phl p 5-sensitized mice
D. Bach, R. Weiss, M. Hessenberger, S. Kitzmueller, E.E. Weinberger, W.D. Krautgartner, C. Hauser-Kronberger, C. Boehler, J. Thalhamer, S. Scheiblhofer
European Journal of Allergy and Clinical Immunology, Nov 2012; 67(11): 1365-1374, DOI: 10.1111/all.12005
Transcutaneous vaccination via laser microporation
R. Weiss, M. Hessenberger, S. Kitzmueller, D. Bach, E.E. Weinberger, W.D. Krautgartner, C. Hauser-Kronberger, B. Malissen, C. Boehler, Y.N. Kalia, J.Thalhamer, S. Scheiblhofer
J Control Release 2012. September 2012; 162(2): 391-399
Erbium:YAG fractional laser ablation for the percutaneous delivery of intact functional therapeutic antibodies
J Yu, DR Kalaria, YN Kalia
J Control Release, Nov. 2011; 156(1):53-9, DOI: 10.1016/j.conrel.2011.04.024, PMID: 21803083
Using laser microporation to improve transdermal delivery of diclofenac: Increasing bioavailability and the range of therapeutic applications.
Bachhav YG, Heinrich A, Kalia YN.
Eur J Pharm Biopharm. 2011 Aug; 78(3):408-14. Epub 2011 Mar 21.
PMID: 21397689
Using controlled laser-microporation to increase transdermal delivery of prednisone.
Yu J, Bachhav YG, Summer S, Heinrich A, Bragagna T, Boehler C, Kalia YN.
J Control Release. 2010 Nov 20; 148(1):e71-3. No abstract available.
PMID: 21529638
Effect of controlled laser microporation on drug transport kinetics into and across the skin.
Bachhav YG, Summer S, Heinrich A, Bragagna T, Boehler C, Kalia YN.
J Control Release. 2010 Aug 17; 146(1):31-6. Epub 2010 May 25.
PMID: 20678988
Noninvasive Transdermal Iontophoretic Delivery of Biologically Active Human Basic Fibroblast Growth Factor
S. Dubey, R. Perozzo, L. Scapozza, YN Kalia
Molecular Pharmaceutics Aug. 2011; 8(4):1322-31, DOI: 10.1021/mp200125j, PMID: 21696184
Development and validation of an analytical method for the quantification of cytochrome c in skin transport studies
YG. Bachhav, YN. Kalia
Biomedical Chromatography, July 2010, 24(7):732-6, DOI:10.1002/bmc 1356
